QC-REQ-IDX Orientation

This page provides orientation and explanatory context for the Quality Control Requirements Index (QC-REQ-IDX). It is intended to support inspections, audits, and onboarding of Quality leadership by explaining how Quality Control requirements are structured and governed.

Inspection Support Notice
This page is explanatory only. It does not define requirements, acceptance criteria, or procedures and is not a controlled GMP specification.

1. What Is the QC-REQ-IDX?

The QC-REQ-IDX is a master index of Quality Control requirements. Each entry in the index links to a single authoritative Quality Control specification that defines acceptance criteria and decision authority for a specific quality domain.

The QC-REQ-IDX does not replace SOPs, records, or systems. Instead, it provides a structured map of what must be true for quality decisions to be made.

2. What a QC-REQ Represents

Each QC-REQ ID represents a discrete Quality Control requirement governed by the Quality Unit.

QC-REQs are intentionally written at a governance level to ensure clarity of authority and consistency across operations.

3. Relationship Between Specifications, SOPs, and Records

The Quality Control documentation hierarchy is structured as follows:

Specifications do not describe execution steps, and SOPs do not redefine requirements.

4. Quality Unit Authority

All QC-REQ specifications are owned and governed by the Quality Unit. Final determinations regarding acceptance, disposition, data usability, and change approval reside with the Quality Unit.

This structure ensures that quality decisions are made based on reviewed evidence and defined criteria rather than informal practice or individual discretion.

5. Change and Continuous Improvement

QC-REQ specifications are subject to formal change control. Changes are evaluated for impact and risk, supported by appropriate validation or verification, and reviewed for effectiveness.

Continuous improvement activities are governed to ensure that enhancements do not introduce uncontrolled risk or erode compliance.

6. How This Page Is Used During Inspection

This orientation page may be referenced to provide context on how Quality Control requirements are organized and governed. Inspectors may then select specific QC-REQs, specifications, SOPs, or records for detailed review.

This page is provided for clarity and navigation only. It does not introduce new GMP requirements or replace controlled Quality documents.