Packaging Environmental Control Specification

This specification defines the Quality Unit–approved environmental acceptance criteria and decision requirements for GMP-designated packaging areas.

Specification Type:
Authoritative Quality Control specification defining environmental acceptance criteria and decision logic. This document does not define execution steps, monitoring methods, or procedural instructions.

1. Purpose

To establish Quality Unit–approved temperature and relative humidity acceptance criteria for packaging operations, ensuring that environmental conditions do not adversely impact product quality, packaging integrity, or labeling throughout GMP packaging activities.

2. Scope

This specification applies to all GMP-designated packaging areas where finished products, components, labels, or packaging materials are exposed during packaging, labeling, or related handling activities.

Applicable Business Domains include:

3. Ownership & Governance

Environmental acceptance criteria and decision thresholds defined in this specification shall not be modified outside approved QMS change control.

4. Environmental Acceptance Criteria

Parameter Acceptance Criteria Applicability
Temperature 15°C – 25°C All GMP-designated packaging areas
Relative Humidity ≤ 60% RH All GMP-designated packaging areas unless otherwise specified by product- or material-specific requirements

5. Decision Logic

6. Escalation Requirements

Quality Assurance must escalate to Quality Control or QCO when any of the following conditions are met:

7. Records & Evidence

Records supporting compliance with this specification include, but are not limited to:

This specification defines acceptance criteria and decision authority only. Procedures, work instructions, and monitoring methods are maintained in separate controlled documents and shall not redefine the requirements herein.